Interpretive Summary: Impacts of Mycoplasma loads and lung lesions on immune and hematological statuses of pigs
By Anne Zinn
Respiratory disease, often accompanied by infections of bacteria, severely affects the pig production industry; Enzootic pneumonia in pigs is a type of respiratory disease that links to infection of pathogenic bacteria, such as Mycoplasma pneumoniae, and is accompanied by lung lesions. While various research has been conducted, there is limited research that focuses on the link between immune and hematological responses of pigs to respiratory disease and bacterial infection. A recent study published in the Journal of Animal Science investigated the correlation of lung lesions and Mycoplasma levels with 57 immune and 25 hematological traits measured in 307 pigs. It was hypothesized that the sample size of more than 300 individuals together with broad genetic and phenotypic variations of the population would offer a reasonable strategy to found biologically meaningful associations.
Results of this study showed that the pigs suffered substantial and varied lung lesions, covering on average 40% of the lung, and that the Mycoplasma was the main genus of bacteria that could lead to exacerbation of lung lesions in pigs. These results provide helpful insights into the changes of host immune status in response to Mycoplasma relevant lung diseases and pigs, and this study will continue to aid in the diagnosis of respiratory disease in pigs.